🌿 The NAD+ Battery Switch

Why the 2 p.m. crash feels so unfair

Last Tuesday, my brain hit a 2 p.m. crash so hard I stared at my inbox like it was written in another language. I slept fine, ate a normal lunch, and still felt like my body dropped into low-power mode.

When energy disappears mid-day, it feels personal. Most of the time, it is biology: stress signals, uneven sleep quality, heavy meals, and a long stretch of sitting can push your “battery gauge” down even when you did everything “right.”

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NAD+ in plain words

NAD+ is a helper molecule your cells use to turn food into usable energy and to run repair jobs behind the scenes. People talk about it because NAD+ is tied to how your body handles strain and recovery. If you want the science angle without hype, read The NAD+ booster tug-of-war inside your cells.

NR vs NMN: pick one lane

Most products sold as “NAD+ supplements” use a building block your body can convert into NAD+. Two common options are NR (nicotinamide riboside) and NMN (nicotinamide mononucleotide). Human research is still early, but both show signals that NAD-related markers can rise after use. The simple rule: choose one, use it steadily, and do not stack two bottles aimed at the same target.

The two-week scorecard that keeps you honest

This is a short experiment, not a forever routine. Keep your schedule steady for 14 days: similar bedtime, similar meals, similar caffeine. Each day, write one short line at three times: morning (how hard it feels to start), mid-afternoon (how foggy you feel), and evening (how much energy is left). Add one line after activity: did you bounce back, or did you feel wiped out?

Dosing without drama

Start with the label’s serving size and keep it boring. Trials often use doses in the hundreds of milligrams per day, and some research has tested higher amounts with monitoring. One randomized safety trial used a high dose of NR for a short period and found it was handled well in that setting, while also noting that longer use at that dose needs more study. See The high-dose NR test that surprised scientists.

Buy it like a skeptic

Your two-week notes only mean something if one variable changes. Look for third-party testing and clear labeling with exact amounts. Skip “proprietary blends” that hide doses. Skip products that add a pile of stimulants, because they can mask what is really happening.

Who should pass on this experiment

Talk with a clinician first if you are pregnant, nursing, have active cancer or a recent cancer history, have serious liver or kidney disease, or have gout. Also check with a clinician if you take blood thinners, diabetes medication, or anything processed by the liver. Read The reality-check review on NAD supplements.

What “working” looks like

You are looking for fewer afternoon crashes, a calmer brain during dull tasks, and a smoother recovery after normal movement. If your notes show no meaningful shift after two weeks, that result is useful. Let it go and focus on basics that reliably move the needle: light after waking, movement breaks, and earlier caffeine.

A grounded way to follow the research

Instead of influencer clips, read study listings that show what scientists measure and how long they track people. Start with A real NR study listing that shows the lab markers.